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Cotargeting proteins involved in glutamine metabolism and the stress response under conditions of glutamine depletion would therefore be a promising therapeutic strategy for overcoming adaptive/resistance mechanisms in cancer cells
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Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction
doi: 10.1002/hep.27235 212 DesaiSSTungJCZhouVXGrenertJPMalatoYRezvaniMet al
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